CLINICAL STUDIES
<< Back to Clinical Studies
Source: chromiuminfo.org
Chromium May Improve Body Composition
San Antonio, TX (June 23,
1998)- Dietary supplementation with chromium may lead to
significant improvements in body composition
in moderately overweight subjects, according to a study reported
in Current Therapeutic Research .
The results of new double-blind, placebo controlled clinical
study, in which 122 moderately overweight individuals took
chromium, showed an average loss of 6.2 pounds of body fat
as opposed to
only 3.4 pounds in those individuals in the placebo group.
The new research, reported in the June issue of Current Therapeutic
Research, reinforces results from an earlier clinical trial
and demonstrates that chromium supplementation can play an
important
role in improving body composition. Body composition is determined
by the ratio of fat-free mass versus the amount of fatty tissue
in the body.
"
The data clearly confirm that supplementation with chromium can
lead to significant improvements in body composition resulting
from fat loss, particularly for individuals who may not be as
aggressive in making lifestyle changes such as reducing caloric
intake or increasing their physical activity," says Gilbert
Kaats, Ph.D., of the Health and Medical Research Foundation in
San Antonio, the lead investigator in the study.
Subjects involved in the study were provided 400 micrograms of
chromium or placebo daily. Changes in body fat, fat-free mass,
and weight were measured over a 90-day period. The results of
the study demonstrated a statistically significant reduction
in body fat (and fat mass) in those individuals who took chromium,
without losing any valuable lean body mass.
The authors noted, "It
has been proposed that chromium's positive effect on body composition
is through its ability to
improve insulin utilization, thereby reducing fat deposition
and resulting in improving entry of glucose and amino acids into
muscle cells. Although this study did not attempt to test this
assertion, the findings are consistent with this hypothesis."
Chromium's ability to improve glucose utilization was also the
subject of presentations and discussion at the recent International
Symposium on the Health Effects of Dietary Chromium sponsored
by the Tufts University School of Medicine, the US Department
of Agriculture, and the Chromium Information Bureau, held in
Dedham, Massachusetts.
During the symposium, which drew leading
diabetologists, endocrinologists, scientists, and dietitians,
Dr. William Cefalu, MD, of the University
of Vermont, College of Medicine, presented human data supporting
the hypothesis that chromium has the ability to improve insulin
action in moderately obese non-diabetic subjects.
"
This latest work is important especially since it was conducted
among moderately obese individuals who are at risk of developing
type 2 diabetes," said Dr. Cefalu. "The clinical implications
of this study with regard to the use of chromium supplementation
in pre-diabetic subjects is significant," he concluded.
Dr. Cefalu is currently conducting a trial using chromium as
a supplement to oral hypoglycemic agents in individuals with
type 2 diabetes. Other researchers who attended the Symposium
are also currently conducting separate trials in type 2 diabetic
patients.
It is important to note that dietary supplements are not drugs.
They are not intended to treat, diagnose, prevent, cure, or mitigate
a disease. Consumers and patients who are concerned about a particular
dietary supplement or nutrition product should consult with a
physician, pharmacist, or dietitian before self-medicating.
• Visit our Products page! |